Non-oxidative modification of native low-density lipoprotein by oxidized low-density lipoprotein

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Non-oxidative modification of native low-density lipoprotein by oxidized low-density lipoprotein.

The oxidative modification of low-density lipoprotein (LDL) has been implicated in the pathogenesis of atherosclerosis, although little is known as yet about the precise mechanism of oxidation in vivo. The studies presented here demonstrate that, in the absence of cells or transition metals, oxidized LDL can modify native LDL through co-incubation in vitro such as to increase its net negative c...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1996

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj3160377